Clinical Trial Results: A Clinical Trial Bazaar!

Interpretation of clinical trial results

Evidence from clinical trials is fundamental to ethical medical practice. Along with patient preferences, circumstances, and clinical experience, it is central to effective clinical decision-making. Applying evidence to clinical questions requires filtering in the form of three questions: first, do the trial results reflect true effects of intervention, rather than artifactual ones (validity)? ...

TRIALS ON TRIAL Interpreting the results of a clinical trial

Elements of an interpretation Authors are generally encouraged to summarise which the results and findings are consistent with hypothesis, and to comment on the robustness of drawing conclusions and making recommendations n ex pla I preparing an article reporting a clinical trial, the authors are pected to provide a reasoned interpretation of the results and ce them into a broader clinical cont...

Acupuncture for chronic nonpulsatile tinnitus: A randomized clinical trial

Background: There is challenge to find an effective treatment for tinnitus. Few studies were done on the effects of acupuncture on tinnitus. This study evaluated the effect of acupuncture on chronic non-pulsatile tinnitus. Methods: This randomized double-blind clinical trial was conducted from December 2014 to September 2015. Patients suffering from chronic non-pulsatile tinnitus were randomly...

Is withholding clinical trial results "research misconduct"?

Communicating clinical trial results to research participants.

BACKGROUND Communicating clinical trial results to research participants is seldom accomplished in a timely or an effective manner. OBJECTIVE To evaluate the effectiveness of a plan to communicate results in an industry-sponsored randomized controlled trial for Huntington disease. DESIGN, SETTING, AND PARTICIPANTS Postal survey to research participants at 28 of 41 research sites (including ...